Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2510)
Related Products (2510)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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LIN28 inhibitor LI71 enantiomer
0 ImagesLIN28 inhibitor LI71 enantiomer is the less active enantiomer of LIN28 inhibitor LI71 (HY-123905). LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 μM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 μM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and α/β tubulin and has an inhibitory effect on Plasmodium falciparum.
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Azlocillin
0 ImagesAzlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection.
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Ethylhydrocupreine
0 ImagesEthylhydrocupreine (Optochin) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.
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Flubendazole-d3
0 ImagesCat. No.: HY-B0294SCAS No.: 1173021-08-3Flubendazole-d3 is the deuterium labeled Flubendazole. Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle.
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Gallinamide A TFA
0 ImagesGallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM). Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM). Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM).
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Epimagnolin A
0 ImagesSynonyms: (+)-epi-MagnolinEpimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells.
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Proguanil-d6 hydrochloride
0 ImagesCat. No.: HY-B0806AS1Purity: 98.73%Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.
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β-Hederin
0 ImagesCat. No.: HY-N7489CAS No.: 35790-95-5β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively.
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Thiabendazole-13C6
0 ImagesSynonyms: 2-(4-Thiazolyl)benzimidazole-13C6Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
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Sulcatone (Standard)
0 ImagesSynonyms: 6-Methyl-5-hepten-2-one (Standard)Sulcatone (Standard) (6-Methyl-5-hepten-2-one (Standard)) is the analytical standard of Sulcatone (HY-W010435). This product is intended for research and analytical applications. Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.
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Albendazole sulfoxide-d3
0 ImagesSynonyms: Ricobendazole d3; Albendazole oxide d3Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
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Nitroxynil
0 ImagesNitroxynil is a broad-spectrum veterinary anthelmintic and a substrate of ABCG2. Nitroxynil inhibits ATP production by uncoupling the oxidative phosphorylation process of mitochondria, thereby disrupting the parasite body covering, impairing its motility, and ultimately inducing parasite death. Nitroxynil induces chromosomal aberrations, sister chromatid exchanges and abnormal sperm morphology, and interferes with spermatogenesis. Nitroxynil is widely applicable to studies on fascioliasis, myiasis, Haemonchus spp. infections, and Oestrus ovis infections.
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Pendulone
0 ImagesPendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity.
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13,21-Dihydroeurycomanone
0 Images13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
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Procodazole
0 ImagesSynonyms: Propazol; 2-Benzimidazolepropionic acidProcodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity.
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Melarsonyl
0 ImagesCat. No.: HY-U00295CAS No.: 37526-80-0Synonyms: Melarsonic acidMelarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
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PfDHODH-IN-1
0 ImagesPfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity.
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Niclosamide-13C6
0 ImagesSynonyms: BAY2353-13C6Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
